Study of Thermodynamic Variables to Adsorption of Aldomete Drug (Methyldopa) from its Water Solution on the Nano Zinc Oxide Surface

Ali A Kadhim, Salih M Haddawi, Zainab M Hussein

Abstract


The experiment was carried out to study the adsorption of aldomete on the surface of nano zinc oxide and its effectiveness in drug adsorption which causes poisoning in the case of doses exceeding the usual doses. UV spectroscopy technique was used to follow the concentration of the drug in the water solution after mixing it with 0.1 g of nano zinc oxide, and different solutions of the drug were used to obtain the adsorption isotherm and tested the applicability of the Lancmair and Freundlich equation for isotherm of the adsorption. The effect of temperature was investigated within the range (298 - 328) Kelvin and the best temperature was 298 Kelvin. The effect of time was also investigated within the range (30-180), and it was found that the largest amount of adsorption at time was 180 minutes. The adsorption was studied at pH = 1 and the thermodynamic functions (ΔG, ΔH, ΔS) were calculated, and the effect of ionic intensity on adsorption was studied by adding (0.1 M) of potassium chloride, it was found that the amount of adsorption of the drug on the surface of the nano zinc oxide increased with the presence of salt and showed the study of the ability of nano zinc oxide to adsorption the drug with highly efficiency.

Keywords


Aldomete drug, Nano zinc oxide, Adsorption, Thermodynamic.

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DOI: http://dx.doi.org/10.25258/ijpqa.10.2.17

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