Comparative Study of Hormonal and IL-6 Levels Among Infertile Women With Polycystic Ovary Syndrome and Healthy Women

Lamees M. Al-Janabi

Abstract


Background: The most common endocrine illness that affects older women with childbearing age is Polycystic ovary syndrome (PCOS). The prevalence ranges from 8%-13% according to the definitions used and residents utilized.
Materials and methods: Illness with the infertile ovarian syndrome and a medical referral were studied to Al Hussain Educational Hospital to the infertility center during the period from August to November 2017. The diagnosis of the illness was serene under the supervision of gynecologists and according to clinical indications. Laboratory discovery. This project investigated 80 healthy people and 90 illness with polycystic ovary syndrome. Hormone levels, including prolactin, TSH, FSH and TSH, and blood samples were measured, and the IL-6 level concentration was examined.
Results: Results exemplify that there was no important alteration between illness and controls regarding age, TSH, and prolactin, while the LH and estradiol were suggestively advanced in illness in comparison to controls, P-value less than 0.001. The FSH and progesterone were suggestively lesser in illness as compared to controls, p-value ≤ 0.001. Results displays that there was an important difference of IL-6 altitudes in illness comparison to controls, P-value less than 0.001.
Conclusion: This indicates the close connotation between the ovary and pituitary axis. The polycystic ovary syndrome is an inflammatory illness that will lead to the rise of many inflammatory cytokines such as; IL-6.

Keywords


FSH, IL-6, Infertile, LH, Polycystic ovary syndrome, Prolactin, TSH.

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DOI: http://dx.doi.org/10.25258/ijpqa.10.4.7

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