International Journal of

Pharmaceutical Quality Assurance

ISSN: 0975 9506
Peer Review Journal

doi prefix: 10.25258/ijpqa

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1. Formulation and Process Validation of Clopidogrel Bisulfate 300mg Tablet
Sravani Shilpa.K., MekaAnand Kumar, Senthil Kumar.
Abstract
The purpose of study is to formulate and process validation is to create a robust formulation and to validate all the critical parameters challenged in manufacturing process like dry mixing, blending, lubrication, compression, coating and packing. By comparing the results of above challenged parameters, it shown that all the results of three batch’s had met the pre determine specification and FDA requirement. Finally by seeing the results we can say that the process followed was correct and are as per c GMP requirements.

2. Microbiological Quality Assesment of Some Commercial Herbal Drugs
Nandna Khurana, Rajeev Kr. Sharma, Seema Bhaduria.
Abstract
In present study five drug samples viz Zingiber officinalis, Boerhaavia diffusa, Glycerrhiza glabara, Terminalia arjuna, Terminalia chebula were analysed for microbial load(Total bacterial count & total yeast and mould count) and for specific pathogenic bacteria (E.coli, Salmonella spp, Staphylococcus aureus, Pseudomonas aeruginosa) as per WHO norms(Anonymous 1998). Total bacterial load is higher in four samples of herbal drugs (Zingiber officinalis, Boerhaavia diffusa, Glycerrhiza glabara, Terminalia chebula). The total Yeast and mould count in all five samples is beyond the prescribed limits of WHO while Specific pathogenic bacteria are absent in all five sample of herbal drugs.

 

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