Baldha Shyam Chunilal, Charaniya Jahanvi Sureshbhai, Boda Rutvikkumar Pravinbhai, Parmar Mansukh K
Anas K. Al Makhzoomi, Mu`Ath Q. Al-Ghadi, Juhina Salim Ababneh, Omran H. Alameri
Hinal Doshi, Aditya Seth, Mehul G. Patel
Priyadarshini D, Vishnu Priya H, Prem B, Venkatesan R
Chandrala Kishan Kishorbhai, Rahul Datta Roy, Bhimani Heta Shaileshbhai, Swapan Debbarma
Bharanidharan M, Jayasree S, Rajarajan P, Venkatesan R
Jayasree S, Bharanidharan M, Ranjith Babu R, Priyadarshini D
Patel Hirenbhai Rameshbhai
Nidhi G. Sathwara, Sumeeta T. Soni
Archana Ashish Ashtekar, Ashish Ramakant Ashtekar
Pinkle Desai, Keval Sondager, Rishita Sondager
Gajipara Vimal Shantibhai, Jayadip Patel, Dharmendra Chhaniyara, Rajan Savaliya
Pallab Kr Bhattacharjee, Pranit Kr Choudhary, Kamala Deka
Burulukui Hembram, Pradip Kumar Mandal
Gupta Akhil, Gupta Shalini
Md. Rizwan Ansari, G.V. Padmaja, Juveria Sultana, Ajitha Reddy Edula
Anupama Bais Solanki, Fanindra Singh Solanki, Anurag Dubey
Chikirsha Vijay, Premanshu Arvind, Nishant, N.P. Gupta, K.K. Jha, Kunal Kumar, Anushri Chourasia
Chikirsha Vijay, Premanshu Arvind, Nishant, N.P. Gupta, K.K. Jha, Kunal Kumar, Anushri Chourasia
Shweta Kumari, Prem Prakash
Sunil Kumar, Manish Kumar Jha, Poonam Kumari
Tarali Devi, Pallavi Bordoloi, Prasanta Dihingia
Akshat Suman, Sarsij Naynam
Bhagraj Choudhary
Shashi Bhushan Kumar, Jhillmill Kumari
Rishi Kant, Muni Lal Gupta
Sunil Kumar, Jitendra Kumar
Anamika
Anil Kumar
Shruthi Shree, K. Yaswanthi Reddy, Sindhuri K.
Pramit Kumar Maji, Subhashis Chakraborty, Suranjan Haldar, Prantik Bhattacharya, Debarshi Jana
Susmita Saurav, Richa Jha
Hima Charan1, Reena Sinha2, Gaurav Kumar Sharma
Sadhna Kumari, Anisha Ranjan, Geeta Sinha
Sunil Kumar, Bhagwan Das
Raveendra Kumar, Manish Raj, Prabhat Agrawal
Sharneshwari Reshmi, Ankushe Rohini Dattatraya, Varnit Kaushik, Mahesh Dhotre
Pallaahishek Reddy, Ankushe Rohini Dattatraya, Nivedita, Mohan K Pujar
Observations and Result: The following observations were noted:
- There was no significant difference found in demographic characteristics and parity wise distribution between the two groups.
- P value was not significant in either groups with respect to average maternal heart rate & average systolic blood pressure and average diastolic blood pressure.
- There was a significant difference between mean values of duration of onset of analgesia, duration of action of bolus dose and duration of active labor when Group A compared with Group B (p=0.0001). There was early onset of analgesia and significantly longer duration of action in group B as compared to group A. The duration of labor was significantly shorter in group B as compared to group
- There was no significant difference found in modes of delivery among the two
- There was no significant difference found in FHS and APGAR scores among the two groups.
- There was a significant difference between mean values of Total dose of Inj.Levobupivacaine, and the total number of top ups given when Group A compared with Group B (p=0.001) The total dose of local anesthetics required, and total number of top ups given was less in group B as compared to group A.
- There was a significant difference between mean values of VAS and NRS score at 30 mins as compared to the baseline values in the individual groups. But no significant difference was noted in the VAS and NRS scores between the two
- When compared the complications and side effects among the two groups, overall safety of the patients was observed in both the groups.
Conclusion: In conclusion, Levobupivacaine is an S (-) enantiomer to bupivacaine with a less cardiotoxicity and neurotoxicity and has a promising safety profile for the patients. Clonidine can be considered as a useful adjunct in labour analgesia with Levobupivacaine as it provides early and longer analgesia than Levobupivacaine with fentanyl combination. It also has local anaesthetic sparing effect without any significant side effects.
Ravi Shekhar, Abnish Nandan, Rakesh Kumar
Deepali, Priya, Dilip Kumar
Jitendra Kumar Chaudhary, Pritam Marandi, Kavita Tirkey, Shital Malua
Murugan T.P., Koshy Alan Valiaveetil, Amanda Grace Sajem, Samuel Philip Oommen
Anisha Ranjan, Surabhi, Rakhi Singh, Sweety Sinha
Niharika Anand, Pinky Priya, Anupama Sinha
Indu Khare, Anisha Ranjan, Sunita Singh, Sangeeta Sinha
Pritam Marandi, Kavita Tirkey, Jitendra Kumar Chaudhary, Shital Malua
Srikant Pandey, Pallavi Sharma, Sujit Kumar, Ramji Prasad Singh
Smita Kumari, Sunita Singh, Geeta Sinha
Vivek Kumar, Nishant Singh, Abhishek
Srikant Pandey, Pallavi Sharma, Akhilesh Kumar, Ramji Prasad Singh
Shipra Singh, Ranjan Kumar Rajan
Ranjan Kumar Rajan, Shipra Singh
Sanjeev Prasad, Dharmdip M. Patel
Dharmdip M. Patel, Sanjeev Prasad
Rahul Kumar Gupta, Sourav Suman, Rajendra Singh
Adity Aarya, Saloni Bharti
Vandana Kumari, Gunjan, Rupam Sinha
Begam Rubia, Anil Kumar, Kumar Saurabh
Padmini Ghosh, Rashmi Sinha, Anupama Sinha
Dhananjay, Amit Kumar, Uday Kumar Udayan
Manish Kumar Jha, Rachna Rani, Nirmal Kumar Mandal, Rambabu Prasad, Ravindra Prasad
Mithilesh Kamal, Harshitha G., Shashi Bhushan Sinha
Sandeep Kumar, Kumar Pravin, Kshitij Raj
Nirmal Kumar Mandal, Rachna Rani, Manish Kumar Jha, Rambabu Prasad, Ravindra Prasad
Chandan Kumar, Swami Nand Prasad, Rajendra Prasad
Vishal Kumar, Rakhi Kumari, Amrita Ghosh Kar
Vishal Kumar, Rakhi Kumari, Amrita Ghosh Kar
Alok Ranjan, Vinod Kumar, Chandra Mohan Sinha
Deepak Kumar Singh, Rajeev Kumar Rajak
Deepak Kumar Singh, Rajeev Kumar Rajak
Amit Kumar, Anuja Bharti, Shyama, Birendra Prasad
Anuja Bharti, Amit Kumar, Birendra Prasad, Shyama
Shyama Nivas, Vinita Sahay
Rituraj, Akhalesh Kumar, Pradeep Kumar Singh
Rituraj, Akhalesh Kumar, Pradeep Kumar Singh
Shyama Nivas, Vinita Sahay
Ajay Chaudhri, Om Prakash, Anil Kumar Sinha, Bijoy Kumar
Manazir Hasan Rahmani, Navin Kumar, Rizwan Haidar, Ashok Kumar
Vikram Jha, Anil Kumar
Ashutosh Kumar, Ashok Kumar
Ashutosh Kumar, Ashok Kumar
Om Prakash, Anil Kumar Sinha, Ajay Chaudhri, Bijoy Kumar
Ranjeet Kumar, Asim Mishra
Rajesh Kumar, Sushil Kumar Pathak, Suman Kumari, Bir Prakash Jaiswal
Rahul Priyadarshi, Archana Kumari, Rizwan Ahmar
Archana Kumari, Rahul Priyadarshi, Jugal Kishore
Saurabh Kumar, Nikesh Kumar, Shantam Mohan, Ramesh Kumar, Shyama
Shweta Kumari, Prem Prakash
Puja Bharti, Shweta Kumari
Nikesh Kumar, Saurabh Kumar, Shantam Mohan, Ramesh Kumar, Shyama
Himanshu Singh, Neelu Raj, Seema Jain, Sparsh Gupta
Neelu Raj, Himanshu Singh, Sparsh Gupta
Punkesh Kumar
Punkesh Kumar
Dinesh Kumar, Ravindra Prasad
Dinesh Kumar, Ravindra Prasad
Kumar Utkarsh, Raman Baliyan
Ashutosh Kumar
Amritesh Kumar
Amritesh Kumar
Sheetal Chandra, Garima Kumari, Manoj Kumar, Rajiv Ranjan Das
Manoj Kumar, Sheetal Chandra, Garima Kumari, Rajiv Ranjan Das
Garima Kumari, Manoj Kumar, Sheetal Chandra, Rajiv Ranjan Das
Indrajit Gupta, Mrigendra Kumar Rai
Vijay Kumar Gupta, Rajesh Kumar
Shambhavi, Anshupriya, Vinayak Gautam
Shambhavi, Anshupriya, Vinayak Gautam
Gajula Sai Kishore, Haridas Somayaji, Vikram Shetty
Beereshwar Prasad, Chandeshwar Chaudhary
Beereshwar Prasad, Chandeshwar Chaudhary
Amit Chaubey, Hima Charan, Reena Sinha
Survind Kumar, Ranvijay Kumar, N.P. Narain
Ambuj, Jyoti Kumar Singh
Jyoti Kumari
Ranvijay Kumar, Survind Kumar, N.P. Narain
Sidhartha Sohan, Sandeep Anand, C. K. Das
Sidhartha Sohan, Sandeep Anand, C. K. Das
Neelam Kumari, Alka Pandey, Manisha
Neelam Kumari, Alka Pandey, Manisha
Randhir Kumar, Swami Nand Prasad, Rajendra Prasad
Rashmi
Rashmi
Ravi Kant, Vikash Kumar
Ravi Kant, Vikash Kumar
Ravi Kant, Vikash Kumar
- Group R received epidural ropivacaine 0.2% at 6 mL/hour.
- Group RT received ropivacaine 0.2% with tramadol 1 mg/mL at the same infusion rate.
General anaesthesia protocols were standardized across both groups. Postoperative pain intensity was assessed using a 10-point visual analogue scale (VAS) at 2, 4, 8, 12, 24, and 48 hours. Rescue analgesia (intravenous morphine 2 mg) was administered for VAS > 4, and cumulative morphine consumption was recorded. Hemodynamic parameters, sedation scores, and adverse events (nausea, vomiting, pruritus, respiratory depression) were monitored throughout the 48-hour postoperative period. Results: Both groups were comparable in demographic and intraoperative variables. Group RT demonstrated significantly lower mean VAS scores at all time points beyond 4 hours postoperatively (p < 0.05). The total morphine requirement in the first 48 hours was reduced by 35% in Group RT compared to Group R (mean ± SD: 8.2 ± 2.4 mg vs. 12.6 ± 3.1 mg; p < 0.001). Hemodynamic stability was maintained in both groups, with no clinically significant differences. Incidence of nausea and vomiting was slightly higher in Group RT (15% vs. 8%), though not statistically significant. No cases of respiratory depression or pruritus were observed. Conclusions: Adding tramadol to epidural ropivacaine significantly enhances postoperative analgesia and reduces opioid requirements in adult patients following abdominal surgery, without compromising hemodynamic stability. This combination may be considered an effective and safe option for postoperative pain management in this population.